At one point or another of our lives, most or all of us have become angry. Whether it is a challenging day or otherwise small things in our life, these can make our patience go away in seconds and leading to an angry outburst.
There is a wide range of anger one can have. You may be one of those who can keep their cool for a long time without getting angry, but you can be the other person, the problematic one, just like me, who is triggered by anything not going according to mood and wish. These leads to impulsivity.
The angrier such person gets, the more he is likely to act impulsively. Scientists are trying to connect the relation between anger and impulsiveness, but in more than 90 % of cases, we tend to act without thinking when we are angry. This may lead to some disastrous consequences, which we regret later on.
Such psychiatric disorders affect our work, daily life, decreasing the quality of life. We want to tell you that the number of people with mental illness is increasing throughout the world to our knowledge and research. [1] Therefore, searching for more effective and easily available treatments and techniques for such illnesses is the need of the day.
Many drugs are found in the market, playing an important role in the treatment of mood disorder. But there are always the complaints that drugs are not effective in all patients, and also these are associated with multiple adverse effects.
One of the major drawbacks of these drugs is tolerance if being used for too long. So, many people in developing and developed countries are turning to the use of natural remedies.
With few or no side effects, no interactions with other medicines and herbal remedies, and with no contraindications with pre-existing conditions, the use of herbal supplements and medications is increasing daily.
Among complementary and alternative medicine (CAM) therapies, herbal medicine is the most commonly used form. [2] It has been observed in a study that the use of herbal supplements was more prevalent in patients with psychiatric disorders. [3] Before discussing the various astonishing effects of herbal supplements, lets first have a brief look at what they are.
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What are Herbs? What is Herbal Medicine/Herbal Supplement?
Plants or plants with savory, aromatic properties and valued for their medicinal qualities are termed as herbs.
Herbal medicines or remedies consist of naturally occurring plant-derived products with little or no industrial processing used to treat illness at local or regional practices. These may include unpurified plant extracts that may work together synergistically to aim for curing illness.
Any part of the plant can be used in the process, but the most commonly used parts are the leaves, seeds, roots, and flowers.
There are different routes of administering these herbal medicines, including eating, drinking, swallowing, inhaling, or applying topically. These herbal medicines contain various biochemicals often termed as "active ingredients" or "active principles." Their presence in the remedy depends on the harvest, soil type, species, and how herbs have been prepared.
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Herbal Psychopharmacology
Keeping in view the complexity of psychiatric disorders, we know that targeting a single mechanism would not be enough. There is a need for multiple antipsychotic effects to be present in a product. Therefore, herbal supplements tend to trigger various action mechanisms to pursue this goal of treating mental disorders, including anger outbursts, depression, anxiety, and many others.
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Antidepressants
1. Hypericum perforatum:
Also known as St. John’s wort, this herb has been used for mental health problems for centuries. A review done in 2016 has proved that St. Jon's wort was more helpful and effective in treating major depressive disorder against placebo. [4] However, it should only be used in mild to moderate depression cases, not moderate to severe depression cases.
2. Bacopa:
This plant, which is also known as Brahmi, is a traditional Indian medicinal plant. It is helpful in anxiety, depression and attention deficit hyperkinetic disorder (ADHD). It affects certain brain chemicals that have a role in thinking, memory, and learning. It has positive mood effects, stress reduction associated with cortisol levels, and has adaptogenic and nootropic effects.[5]
Various supplements are present in the market that contain this herbal component and help stay alert and focused. Spark is a stunning blend of this herb with others like GABA, green tea extract, Huperzine A, and many others for producing top of class supplements to boost your day with its astonishing effects. With its amazing constituents of herbs with useful effects, it is a must-have supplement for just in case.
3. Ginseng:
For centuries, this herb has been used in the Chinese culture for elevating mood and keeping healthy. A compound 20(S)-protopanaxadiol present in ginseng has been proved to be of an antidepressant by increasing Norepinephrine and 5-HT in the brain of rats [6].
4. Peony:
It is the root portion of a plant Paeonia lactiflora Pall. After processing, it has been a part of various Chinese herbal medications to treat the depressive disorder. Many studies also suggested its antidepressant activity in rodents through total glyceride fraction of peony (TGP) and ethanol extract [7], [8]. Chronic unpredictable stress cause depressive symptoms, which are treated by the antidepressant activity of TGP by inhibition of monoamine oxidases [9]
5. Mimosa:
Albizia julibrissin or silk tree was found to show antidepressant activity at the dose of 200mg/kg by methylene chloride fraction of Albizia julibrissin (MCAJ). [10]
6. Icariin:
It is a principal flavonoid present in Epimedium (a kind of herb). It reduces the stress level by decreasing elevated corticosterone. So, it restores the normal function and expression of GR and exerts its antidepressant activity. [11]
7. Fuzi: Radix Aconiti Lateralis Preparata:
This herb or its other constituents has been used in practice for depression. Alkaloids from Fuzi increase the phosphorylation of CREB (CAMP response element-binding protein) and expression of BDNF and giv3 anti-depressants like results. [12]
8. Rhodiola Rosea:
This perennial plant extract is used to lessen anxiety, stress, fatigue, and anoxia. It improves immune function, central nervous system, and cardiovascular system.[13] Further study suggests that this herb has a useful effect on mental status in stress.
9. Saffron:
This herbal medicine is consisting of both saffron and crocin. Crocin decease/inhibit the reuptake of dopamine and norepinephrine; also, saffron decrease/inhibit the reuptake of serotonin and exerts antidepressant activity. It also lessens the depressive symptoms through the NMDA receptor.[14], [15]
Saffron is an amazing herb with established use all over the world. It is a potential herb and has sound scientific evidence about its anti-depressive effects. [16] Some studies suggest that taking saffron is as effective as taking some prescription drugs. And taking saffron with some of these medications proved to be more effective in reducing depression than taking medication alone.
Be Herbal Pure Saffron is an all-natural saffron extract that happens to have all the stunning effects of saffron, from improving vision to reducing appetite. It is a bad mood, anxiety, and depression fighter. It helps in a calming and soothing sleep with helping to get desired sleep cycles with no stimulants, caffeine, or hormones used, this product in 100% safe to use with almost no side effect.
10. Bupleurum:
Current research has suggested that Bupleurum chinence is a harmonious herb and is proven to contain antidepressant activity. Many mechanisms regulate its anti-depressant like effect. [17] B. yinchowense is helpful in various conditions like giving vital energy to organs like the spleen, stomach, and liver. It has healing properties in mental disorders like anxiety, depression, and fear. [18]
Anxiolytics
Anxiolytic drugs like SSRIs, SNRIs, benzodiazepines, and many other such drugs are used widely, but these have many adverse effects, and tolerance is developed after some time. The use of plant products and natural extracts is gaining enough interest.
1. Ashwagandha:
It is an adaptogen herb and is and is used in response to stress and anxiety. It does so by having effects on cortisol level and adrenaline. It helps out the sufferers of post-traumatic patients with an anxiety disorder. Studies suggest that ashwagandha against placebo was of considerable importance and helps establish the calming effects of this herb. [19]
Some of the best herbal supplements are present there containing Ashwagandha, which helps reduce stress, calming, regaining energy, and vitality. This product provides a premium grade guarantee and is produced in the U.S based GMP certified facility with 3rd party testing.,
2. Kamishoyoson:
This Kampo formula, which consists of 10 herbs, including Gardeniae Fructus, could be used to alleviate the anxiety symptoms, especially in menopausal psychotic syndromes. Research indicates that the Gardeniae Fructus and geniposide present partly the anxiolytic effects and increase social interaction duration.[20]
3. Ginkgo Biloba Leaves:
As one of the oldest plants, Ginkgo Biloba is a famous Chinese herb used to treat anxiety. The extract of these leaves (EGB) at high concentrations can inhibit the uptake of neurotransmitters in the brain of rats, and EGB 761 can alleviate anxiety symptoms in people with mental disease.
4. Kava:
Kava has been reported to be extremely helpful in treating anxiety, but there are reports of liver damage associated with kava use; therefore, the FDA issued warnings about its use.
5. Zizyphi Spinosi Semen (ZSS):
Its dried seeds have been used in Asia for anxiety and insomnia. Sanjoinine, the principal alkaloid constituent of ZSS, exerts its anxiolytic effect by activating Cl-channels and GABA-benzodiazepine receptors.[21] So, Sanjoinine can be summed up as a good drug candidate for treating anxiety.
6. Chamomile:
Short term use of chamomile helps reduce the symptoms of anxiety. It contains apigenin along with many other constituents, which can alleviate anxiety symptoms by influencing GABA.
7. Lavender:
Oral Lavender or lavender with aromatherapy can help reduce the symptoms of anxiety.
Hypnotics
Insomnia is one of the major sleep disorders of the modern world. According to a survey, one-third of the population is suffering from sleep disorders and wakefulness. [22] These disorders can lead to stress and depression and ultimately, outburst in daily life.
Many mechanisms are involved in sleep disorder, including GABA receptors, cortisol, cytokines, circadian rhythms. Many herbal medicines, supplements, and complexes are used for such disorders.
1. Semen Ziziphi Spinosae (SZS)/Suan Zao Ren:
Though most commonly prescribed worldwide, especially in Japan, Korea, and other oriental countries, this herb has an active compound Jujoboside A (JuA). It improves sleep quality by prolonging sleep time and increasing rapid eye movement (REM) sleep. It appeared to be a safe choice in patients for sedation/hypnosis.[23]
2. Valeriana officianalis L/Valerianaceae:
These extracts of Valerian and valerinic acid are the activators of 5-HT5a receptors and are used to treat restlessness and insomnia. Valerian helps to fall sleep by mimicking the effect of adenosine.[24]
3. Lactuca Sativa:
Also known as garden lettuce and member of the Compositae family is commonly used as a salad in herb and has been used as a sleeping pill for centuries. It was also used to alleviate pain and inflammation. [25]
4. Saffron:
The stigma of Crocus sativus L has many effects on the central nervous system. The water extract of saffron has exhibited many neuropharmacological effects in the mice. These studies suggested the anxiolytic and hypnotic properties of saffron aqueous extract and safranal.
One of the best herbal supplements found out to solve all your problems together is Be Herbal Chill Pill. Made under the supervision of our extremely well-equipped scientists and researchers in certified facilities, this formula contains all you need.
Containing all astonishingly beneficial herbs like Ashwagandha, St. Johns Wort, Chamomile, Lemon Balm, Bacopa, Valerian, Magnolia, Passion flower, and many others, this product is a wonder. It increases focus and clarity by relaxing and calming the body and mind. With all those revitalizing drugs, it is full of positive energy and is anxiolytic and anti-depressive.
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